Research

Research coming out of our lab utilizes multivariate methods we developed to characterize the emergent genetic signal for human complex traits. Our empirical applications focus on psychiatric disorders, neurodegenerative disorders, and cognitive aging. With that said, our extensive collaborative and international network (highlighted below in interactive network plot) has resulted in partnerships to help apply methods with researchers who bring etiological expertise for a wide-range of outcomes, including heart disease, chronic pain, immune-mediated conditions, and medical outcomes more generally.

Highlighted

Mapping the genetic landscape across 14 psychiatric disorders

Andrew D. Grotzinger, Josefin Werme, Wouter J. Peyrot, Oleksandr Frei, Christiaan de Leeuw, …, Hang Zhou, Peter Zill, Phil H. Lee, Kenneth S. Kendler, Jordan W. Smoller

Nature  ·  10 Dec 2025  ·  doi:10.1038/s41586-025-09820-3

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Andrew D. Grotzinger, Mijke Rhemtulla, Ronald de Vlaming, Stuart J. Ritchie, Travis T. Mallard, …, Ian J. Deary, Philipp D. Koellinger, K. Paige Harden, Michel G. Nivard, Elliot M. Tucker-Drob

Nature Human Behaviour  ·  08 Apr 2019  ·  doi:10.1038/s41562-019-0566-x

Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling

Isabelle F. Foote, Jonny P. Flint, Anna E. Fürtjes, Jeremy M. Lawrence, Donncha S. Mullin, …, Janice M. Ranson, Simon R. Cox, Michelle Luciano, Kenneth Rockwood, Andrew D. Grotzinger

Nature Genetics  ·  01 Aug 2025  ·  doi:10.1038/s41588-025-02269-0

Articles Authored by Mentees

Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling

Isabelle F. Foote, Jonny P. Flint, Anna E. Fürtjes, Jeremy M. Lawrence, Donncha S. Mullin, …, Janice M. Ranson, Simon R. Cox, Michelle Luciano, Kenneth Rockwood, Andrew D. Grotzinger

Nature Genetics  ·  01 Aug 2025  ·  doi:10.1038/s41588-025-02269-0

Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders

Sophie Breunig, Younga Heather Lee, Elizabeth W. Karlson, Arjun Krishnan, Jeremy M. Lawrence, Lukas S. Schaffer, Andrew D. Grotzinger

Translational Psychiatry  ·  21 Jul 2025  ·  doi:10.1038/s41398-025-03470-9

Multivariate genomic analyses of frailty reveal the unique importance of cognitive and multimorbidity pathways for aging‐related health outcomes

Isabelle F Foote, Jonny P Flint, John D Fisk, Tobias K Karakach, Andrew Rutenberg, …, Michelle K Lupton, Simon R Cox, Michelle Luciano, Kenneth Rockwood, Andrew D Grotzinger

Alzheimer's & Dementia  ·  09 Jan 2025  ·  pmc:PMC11714510

Characterizing genetic pathways unique to autism spectrum disorder at multiple levels of biological analysis

Lukas S. Schaffer, Sophie Breunig, Jeremy M. Lawrence, Isabelle F. Foote, Andrew D. Grotzinger

Molecular Autism  ·  15 Oct 2024  ·  doi:10.1186/s13229-024-00624-2

Examining Differences in the Genetic and Functional Architecture of Attention-Deficit/Hyperactivity Disorder Diagnosed in Childhood and Adulthood

Sophie Breunig, Jeremy M. Lawrence, Isabelle F. Foote, Hannah J. Gebhardt, Erik G. Willcutt, Andrew D. Grotzinger

Biological Psychiatry Global Open Science  ·  01 May 2024  ·  doi:10.1016/j.bpsgos.2024.100307

Genomic SEM applied to explore etiological divergences in bipolar subtypes

Jeremy M. Lawrence, Sophie Breunig, Isabelle F. Foote, Connor B. Tallis, Andrew D. Grotzinger

Psychological Medicine  ·  27 Oct 2023  ·  doi:10.1017/s0033291723002957

Additional Works

Characterizing the Pleiotropic Architecture of Impulsivity and Its Links to Psychopathology and Neurodevelopment

Travis T. Mallard, Justin D. Tubbs, Mariela Jennings, Yingzhe Zhang, Daniel E. Gustavson, …, Karmel W. Choi, Tian Ge, Jordan W. Smoller, Abraham A. Palmer, Sandra Sanchez-Roige

American Journal of Psychiatry  ·  01 Jan 2026  ·  doi:10.1176/appi.ajp.20240382

Mapping the genetic landscape across 14 psychiatric disorders

Andrew D. Grotzinger, Josefin Werme, Wouter J. Peyrot, Oleksandr Frei, Christiaan de Leeuw, …, Hang Zhou, Peter Zill, Phil H. Lee, Kenneth S. Kendler, Jordan W. Smoller

Nature  ·  10 Dec 2025  ·  doi:10.1038/s41586-025-09820-3

A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders

Olav B. Smeland, Gleda Kutrolli, Shahram Bahrami, Vera Fominykh, Nadine Parker, …, Srdjan Djurovic, Anders M. Dale, Alexey A. Shadrin, Oleksandr Frei, Ole A. Andreassen

Nature Neuroscience  ·  11 Nov 2025  ·  doi:10.1038/s41593-025-02090-2

Modeling the genomic architecture of adiposity and anthropometrics across the lifespan

Christopher H. Arehart, Meng Lin, Raine A. Gibson, Heather D. Anderson, Christina L. Aquilante, …, Sridharan Raghavan, Christopher R. Gignoux, Maggie A. Stanislawski, Andrew D. Grotzinger, Luke M. Evans

Nature Communications  ·  13 Aug 2025  ·  doi:10.1038/s41467-025-62730-w

Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI

Anna E. Fürtjes, Isabelle F. Foote, Charley Xia, Gail Davies, Joanna Moodie, …, Michelle Luciano, W. David Hill, Ian J. Deary, Elliot M. Tucker-Drob, Simon R. Cox

Nature Communications  ·  21 Jul 2025  ·  doi:10.1038/s41467-025-61978-6

Comparison of the multivariate genetic architecture of eight major psychiatric disorders across sex

Ted Schwaba, Travis T. Mallard, Adam X. Maihofer, Mijke Rhemtulla, Phil H. Lee, Jordan W. Smoller, Lea K. Davis, Michel G. Nivard, Andrew D. Grotzinger, Elliot M. Tucker-Drob

Nature Genetics  ·  01 Mar 2025  ·  doi:10.1038/s41588-025-02093-6

Correction: Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research

Na Cai, Brad Verhulst, Ole A. Andreassen, Jan Buitelaar, Howard J. Edenberg, …, John I. Nurnberger, Wouter J. Peyrot, Elliot M. Tucker-Drob, Jordan W. Smoller, Kenneth S. Kendler

Molecular Psychiatry  ·  28 Jan 2025  ·  doi:10.1038/s41380-025-02914-4

Impulsivity facets and substance use involvement: insights from genomic structural equation modeling

Laura Vilar-Ribó, Alexander S. Hatoum, Andrew D. Grotzinger, Travis T. Mallard, Sarah Elson, Pierre Fontanillas, Abraham A. Palmer, Daniel E. Gustavson, Sandra Sanchez-Roige

Psychological Medicine  ·  01 Jan 2025  ·  doi:10.1017/s0033291725000145

Examining the genetic relationship between Alzheimer’s disease, schizophrenia and their shared risk factors using genomic structural equation modelling

Inês Almeida e Sousa, Andrew D Grotzinger, Jeremy M Lawrence, Sophie Breunig, Charles R Marshall, Ania Korszun, Isabelle F Foote

Brain Communications  ·  01 Jan 2025  ·  doi:10.1093/braincomms/fcaf112

Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research

Na Cai, Brad Verhulst, Ole A. Andreassen, Jan Buitelaar, Howard J. Edenberg, …, John I. Nurnberger, Wouter J. Peyrot, Elliot M. Tucker-Drob, Jordan W. Smoller, Kenneth S. Kendler

Molecular Psychiatry  ·  27 Dec 2024  ·  doi:10.1038/s41380-024-02878-x

Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Richard Karlsson Linnér, Travis T. Mallard, Peter B. Barr, Sandra Sanchez-Roige, James W. Madole, …, Irwin D. Waldman, Abraham A. Palmer, K. Paige Harden, Philipp D. Koellinger, Danielle M. Dick

Nature Neuroscience  ·  06 Dec 2024  ·  doi:10.1038/s41593-024-01853-7

Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts

Mark J. Adams, Jackson G. Thorp, Bradley S. Jermy, Alex S. F. Kwong, Kadri Kõiv, …, Naomi R. Wray, Elliot M. Tucker-Drob, Cathryn M. Lewis, Andrew M McIntosh, Eske M. Derks

Psychological Medicine  ·  01 Sep 2024  ·  doi:10.1017/s0033291724001880

Genetic associations between non-cognitive skills and academic achievement over development

Margherita Malanchini, Andrea G. Allegrini, Michel G. Nivard, Pietro Biroli, Kaili Rimfeld, …, Javier De la Fuente, Jean-Baptiste Pingault, Elliot M. Tucker-Drob, K. Paige Harden, Robert Plomin

Nature Human Behaviour  ·  26 Aug 2024  ·  doi:10.1038/s41562-024-01967-9

Partitioning the Genomic Components of Behavioral Disinhibition and Substance Use (Disorder) Using Genomic Structural Equation Modeling

Tanya B. Horwitz, Katerina Zorina-Lichtenwalter, Daniel E. Gustavson, Andrew D. Grotzinger, Michael C. Stallings

Behavior Genetics  ·  09 Jul 2024  ·  doi:10.1007/s10519-024-10188-9

Evidence for strong genetic correlations among internalizing psychopathology and related self-reported measures using both genomic and twin/adoptive approaches.

Daniel E. Gustavson, Elisa F. Stern, Chandra A. Reynolds, Andrew D. Grotzinger, Robin P. Corley, Sally J. Wadsworth, Soo H. Rhee, Naomi P. Friedman

Journal of Psychopathology and Clinical Science  ·  01 Jul 2024  ·  doi:10.1037/abn0000905

Disentangling differing relationships between internalizing disorders and alcohol use

Maizy S. Brasher, Andrew D. Grotzinger, Naomi P. Friedman, Harry R. Smolker, Luke M. Evans

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics  ·  20 Feb 2024  ·  doi:10.1002/ajmg.b.32975

Beyond the factor indeterminacy problem using genome-wide association data

Margaret L. Clapp Sullivan, Ted Schwaba, K. Paige Harden, Andrew D. Grotzinger, Michel G. Nivard, Elliot M. Tucker-Drob

Nature Human Behaviour  ·  15 Jan 2024  ·  doi:10.1038/s41562-023-01789-1

Genetic associations between alcohol phenotypes and life satisfaction: a genomic structural equation modelling approach

Kaitlin E. Bountress, Shannon E. Cusack, Sage E. Hawn, Andrew Grotzinger, Daniel Bustamante, Robert M. Kirkpatrick, Howard J. Edenberg, Ananda B. Amstadter

Scientific Reports  ·  18 Aug 2023  ·  doi:10.1038/s41598-023-40199-1

Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes

Varun Warrier, Eva-Maria Stauffer, Qin Qin Huang, Emilie M. Wigdor, Eric A. W. Slob, …, Aaron Alexander-Bloch, Hyejung Won, Hilary C. Martin, Edward T. Bullmore, Richard A. I. Bethlehem

Nature Genetics  ·  17 Aug 2023  ·  doi:10.1038/s41588-023-01475-y

Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing

Andrew D. Grotzinger, Kritika Singh, Tyne W. Miller-Fleming, Max Lam, Travis T. Mallard, Yu Chen, Zhaowen Liu, Tian Ge, Jordan W. Smoller

JAMA Psychiatry  ·  01 Aug 2023  ·  doi:10.1001/jamapsychiatry.2023.1808

Genetic risk shared across 24 chronic pain conditions: identification and characterization with genomic structural equation modeling

Katerina Zorina-Lichtenwalter, Carmen I. Bango, Lukas Van Oudenhove, Marta Čeko, Martin A. Lindquist, Andrew D. Grotzinger, Matthew C. Keller, Naomi P. Friedman, Tor D. Wager

Pain  ·  23 May 2023  ·  doi:10.1097/j.pain.0000000000002922

Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits

Luke M. Evans, Christopher H. Arehart, Andrew D. Grotzinger, Travis J. Mize, Maizy S. Brasher, Jerry A. Stitzel, Marissa A. Ehringer, Charles A. Hoeffer

PLOS Genetics  ·  22 May 2023  ·  doi:10.1371/journal.pgen.1010693

Genetic contributions of noncognitive skills to academic development

Margherita Malanchini, Andrea Allegrini, Michel G Nivard, Pietro Biroli, Kaili Rimfeld, …, Javier de la Fuente, Jean-Baptiste Pingault, K Harden, Elliot Tucker-Drob, Robert Plomin

Springer Science and Business Media LLC  ·  07 Apr 2023  ·  doi:10.21203/rs.3.rs-2775994/v1

Examining the shared etiology of psychopathology with genome-wide association studies

Travis T. Mallard, Andrew D. Grotzinger, Jordan W. Smoller

Physiological Reviews  ·  01 Apr 2023  ·  doi:10.1152/physrev.00016.2022

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Alexander S. Hatoum, Sarah M. C. Colbert, Emma C. Johnson, Spencer B. Huggett, Joseph D. Deak, …, Renato Polimanti, Joel Gelernter, Howard J. Edenberg, Ryan Bogdan, Arpana Agrawal

Nature Mental Health  ·  22 Mar 2023  ·  doi:10.1038/s44220-023-00034-y

Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis

Andrew D. Grotzinger, Travis T. Mallard, Zhaowen Liu, Jakob Seidlitz, Tian Ge, Jordan W. Smoller

Nature Communications  ·  20 Feb 2023  ·  doi:10.1038/s41467-023-36605-x

Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis: A Simple Solution

Andrew D. Grotzinger, Javier de la Fuente, Florian Privé, Michel G. Nivard, Elliot M. Tucker-Drob

Biological Psychiatry  ·  01 Jan 2023  ·  doi:10.1016/j.biopsych.2022.05.029

Potential bias in genetic correlations

Andrew D. Grotzinger, Matthew C. Keller

Science  ·  18 Nov 2022  ·  doi:10.1126/science.ade8002

A Mixed‐Methods Approach to Refining and Measuring the Construct of Positive Risk‐Taking in Adolescence

Megan W. Patterson, Lilla Pivnick, Frank D. Mann, Andrew D. Grotzinger, Kathryn C. Monahan, Laurence D. Steinberg, Benjamin Oosterhoff, Jennifer L. Tackett, Elliot M. Tucker‐Drob, K. Paige Harden

Journal of Research on Adolescence  ·  10 Nov 2022  ·  doi:10.1111/jora.12807

Transcriptome-wide and stratified genomic structural equation modeling identify neurobiological pathways shared across diverse cognitive traits

Andrew D. Grotzinger, Javier de la Fuente, Gail Davies, Michel G. Nivard, Elliot M. Tucker-Drob

Nature Communications  ·  21 Oct 2022  ·  doi:10.1038/s41467-022-33724-9

An in-laboratory stressor reveals unique genetic variation in child cortisol output.

Laurel Raffington, Margherita Malanchini, Andrew D. Grotzinger, James W. Madole, Laura E. Engelhardt, Aditi Sabhlok, Cherry Youn, Megan W. Patterson, K. Paige Harden, Elliot M. Tucker-Drob

Developmental Psychology  ·  01 Oct 2022  ·  doi:10.1037/dev0001393

Integrated analysis of direct and proxy genome wide association studies highlights polygenicity of Alzheimer’s disease outside of the APOE region

Javier de la Fuente, Andrew D. Grotzinger, Riccardo E. Marioni, Michel G. Nivard, Elliot M. Tucker-Drob

PLOS Genetics  ·  03 Jun 2022  ·  doi:10.1371/journal.pgen.1010208

Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

Travis T. Mallard, Richard Karlsson Linnér, Andrew D. Grotzinger, Sandra Sanchez-Roige, Jakob Seidlitz, …, Elliot M. Tucker-Drob, Kenneth S. Kendler, Matthew C. Keller, Philipp D. Koellinger, K. Paige Harden

Cell Genomics  ·  01 Jun 2022  ·  doi:10.1016/j.xgen.2022.100140

Genetic associations with learning over 100 days of practice

Cherry Youn, Andrew D. Grotzinger, Christina M. Lill, Lars Bertram, Florian Schmiedek, Martin Lövdén, Ulman Lindenberger, Michel Nivard, K. Paige Harden, Elliot M. Tucker-Drob

npj Science of Learning  ·  04 May 2022  ·  doi:10.1038/s41539-022-00121-2

Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach

Kaitlin E. Bountress, Leslie A. Brick, Christina Sheerin, Andrew Grotzinger, Daniel Bustamante, …, Ole A. Andreassen, Jurjen Luykx, Arash Javanbakht, Nagy A. Youssef, Ananda B. Amstadter

Drug and Alcohol Dependence  ·  01 May 2022  ·  doi:10.1016/j.drugalcdep.2022.109430

Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis

Andrew D. Grotzinger, Travis T. Mallard, Wonuola A. Akingbuwa, Hill F. Ip, Mark J. Adams, …, Phil H. Lee, Kenneth S. Kendler, Jordan W. Smoller, Elliot M. Tucker-Drob, Michel G. Nivard

Nature Genetics  ·  01 May 2022  ·  doi:10.1038/s41588-022-01057-4

Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts

Travis T. Mallard, Jeanne E. Savage, Emma C. Johnson, Yuye Huang, Alexis C. Edwards, …, Arpana Agrawal, Lea K. Davis, Toni-Kim Clarke, Abraham A. Palmer, Sandra Sanchez-Roige

American Journal of Psychiatry  ·  01 Jan 2022  ·  doi:10.1176/appi.ajp.2020.20091390

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Richard Karlsson Linnér, Travis T. Mallard, Peter B. Barr, Sandra Sanchez-Roige, James W. Madole, …, Irwin D. Waldman, Abraham A. Palmer, K. Paige Harden, Philipp D. Koellinger, Danielle M. Dick

Nature Neuroscience  ·  26 Aug 2021  ·  doi:10.1038/s41593-021-00908-3

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

Jackson G. Thorp, Adrian I. Campos, Andrew D. Grotzinger, Zachary F. Gerring, Jiyuan An, …, Stuart MacGregor, Nicholas G. Martin, Sarah E. Medland, Christel M. Middeldorp, Eske M. Derks

Nature Human Behaviour  ·  15 Apr 2021  ·  doi:10.1038/s41562-021-01094-9

Shared genetic architecture across psychiatric disorders

Andrew D. Grotzinger

Psychological Medicine  ·  17 Mar 2021  ·  doi:10.1017/s0033291721000829

Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction

Perline A. Demange, Margherita Malanchini, Travis T. Mallard, Pietro Biroli, Simon R. Cox, …, Benjamin S. Williams, Eveline L. de Zeeuw, Daniel W. Belsky, K. Paige Harden, Michel G. Nivard

Nature Genetics  ·  01 Jan 2021  ·  doi:10.1038/s41588-020-00754-2

Adolescent Big Five personality and pubertal development: Pubertal hormone concentrations and self-reported pubertal status.

Alithe L. Van den Akker, Daniel A. Briley, Andrew D. Grotzinger, Jennifer L. Tackett, Elliot M. Tucker-Drob, K. Paige Harden

Developmental Psychology  ·  01 Jan 2021  ·  doi:10.1037/dev0001135

A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data

Javier de la Fuente, Gail Davies, Andrew D. Grotzinger, Elliot M. Tucker-Drob, Ian J. Deary

Nature Human Behaviour  ·  07 Sep 2020  ·  doi:10.1038/s41562-020-00936-2

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Ben Brumpton, Eleanor Sanderson, Karl Heilbron, Fernando Pires Hartwig, Sean Harrison, …, Jaakko Kaprio, George Davey Smith, Bjørn Olav Åsvold, Gibran Hemani, Neil M. Davies

Nature Communications  ·  14 Jul 2020  ·  doi:10.1038/s41467-020-17117-4

Genetic Associations Between Executive Functions and a General Factor of Psychopathology

K. Paige Harden, Laura E. Engelhardt, Frank D. Mann, Megan W. Patterson, Andrew D. Grotzinger, …, Megan L. Thibodeaux, Samantha M. Freis, Jennifer L. Tackett, Jessica A. Church, Elliot M. Tucker-Drob

Journal of the American Academy of Child & Adolescent Psychiatry  ·  01 Jun 2020  ·  doi:10.1016/j.jaac.2019.05.006

Weak and uneven associations of home, neighborhood, and school environments with stress hormone output across multiple timescales

Margherita Malanchini, Laura E. Engelhardt, Laurel A. Raffington, Aditi Sabhlok, Andrew D. Grotzinger, …, James W. Madole, Samantha M. Freis, Megan W. Patterson, K. Paige Harden, Elliot M. Tucker-Drob

Molecular Psychiatry  ·  04 May 2020  ·  doi:10.1038/s41380-020-0747-z

“Same but different”: Associations between multiple aspects of self-regulation, cognition, and academic abilities.

Margherita Malanchini, Laura E. Engelhardt, Andrew D. Grotzinger, K. Paige Harden, Elliot M. Tucker-Drob

Journal of Personality and Social Psychology  ·  01 Dec 2019  ·  doi:10.1037/pspp0000224

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Phil H. Lee, Verneri Anttila, Hyejung Won, Yen-Chen A. Feng, Jacob Rosenthal, …, Naomi R. Wray, Daniel H. Geschwind, Benjamin M. Neale, Kenneth S. Kendler, Jordan W. Smoller

Cell  ·  01 Dec 2019  ·  doi:10.1016/j.cell.2019.11.020

Genetic overlap between executive functions and BMI in childhood

Alexis C Wood, Uku Vainik, Laura E Engelhardt, Daniel A Briley, Andrew D Grotzinger, Jessica A Church, K Paige Harden, Elliot M Tucker-Drob

The American Journal of Clinical Nutrition  ·  01 Oct 2019  ·  doi:10.1093/ajcn/nqz109

Testing Cold and Hot Cognitive Control as Moderators of a Network of Comorbid Psychopathology Symptoms in Adolescence

James W. Madole, Mijke Rhemtulla, Andrew D. Grotzinger, Elliot M. Tucker-Drob, K. Paige Harden

Clinical Psychological Science  ·  06 May 2019  ·  doi:10.1177/2167702619842466

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Andrew D. Grotzinger, Mijke Rhemtulla, Ronald de Vlaming, Stuart J. Ritchie, Travis T. Mallard, …, Ian J. Deary, Philipp D. Koellinger, K. Paige Harden, Michel G. Nivard, Elliot M. Tucker-Drob

Nature Human Behaviour  ·  08 Apr 2019  ·  doi:10.1038/s41562-019-0566-x

Genetic and Environmental Links Between General Factors of Psychopathology and Cognitive Ability in Early Childhood

Andrew D. Grotzinger, Amanda K. Cheung, Megan W. Patterson, K. Paige Harden, Elliot M. Tucker-Drob

Clinical Psychological Science  ·  18 Jan 2019  ·  doi:10.1177/2167702618820018

Genetic and environmental influences on internalizing psychopathology across age and pubertal development.

Megan W. Patterson, Frank D. Mann, Andrew D. Grotzinger, Jennifer L. Tackett, Elliot M. Tucker-Drob, K. Paige Harden

Developmental Psychology  ·  01 Oct 2018  ·  doi:10.1037/dev0000578

Genetic and Environmental Associations Between Child Personality and Parenting

Mona Ayoub, Daniel A. Briley, Andrew Grotzinger, Megan W. Patterson, Laura E. Engelhardt, Jennifer L. Tackett, K. Paige Harden, Elliot M. Tucker-Drob

Social Psychological and Personality Science  ·  17 Jul 2018  ·  doi:10.1177/1948550618784890

Developmental differences in reward sensitivity and sensation seeking in adolescence: Testing sex-specific associations with gonadal hormones and pubertal development.

K. Paige Harden, Frank D. Mann, Andrew D. Grotzinger, Megan W. Patterson, Laurence Steinberg, Jennifer L. Tackett, Elliot M. Tucker-Drob

Journal of Personality and Social Psychology  ·  01 Jul 2018  ·  doi:10.1037/pspp0000172

Genetic and environmental influences on pubertal hormones in human hair across development

Andrew D. Grotzinger, Daniel A. Briley, Laura E. Engelhardt, Frank D. Mann, Megan W. Patterson, Jennifer L. Tackett, Elliot M. Tucker-Drob, K. Paige Harden

Psychoneuroendocrinology  ·  01 Apr 2018  ·  doi:10.1016/j.psyneuen.2018.02.005

Hair and Salivary Testosterone, Hair Cortisol, and Externalizing Behaviors in Adolescents

Andrew D. Grotzinger, Frank D. Mann, Megan W. Patterson, Jennifer L. Tackett, Elliot M. Tucker-Drob, K. Paige Harden

Psychological Science  ·  14 Feb 2018  ·  doi:10.1177/0956797617742981

Twin models of environmental and genetic influences on pubertal development, salivary testosterone, and estradiol in adolescence

Andrew D. Grotzinger, Frank D. Mann, Megan W. Patterson, Kathrin Herzhoff, Jennifer L. Tackett, Elliot M. Tucker‐Drob, K. Paige Harden

Clinical Endocrinology  ·  14 Dec 2017  ·  doi:10.1111/cen.13522

Genetic influences on hormonal markers of chronic hypothalamic–pituitary–adrenal function in human hair

E. M. Tucker-Drob, A. D. Grotzinger, D. A. Briley, L. E. Engelhardt, F. D. Mann, …, C. Kirschbaum, E. K. Adam, J. A. Church, J. L. Tackett, K. P. Harden

Psychological Medicine  ·  19 Jan 2017  ·  doi:10.1017/s0033291716003068

Sensation seeking and impulsive traits as personality endophenotypes for antisocial behavior: Evidence from two independent samples

Frank D. Mann, Laura Engelhardt, Daniel A. Briley, Andrew D. Grotzinger, Megan W. Patterson, …, Michael Lynskey, Wendy Slutske, Nicholas G. Martin, Elliot M. Tucker-Drob, K. Paige Harden

Personality and Individual Differences  ·  01 Jan 2017  ·  doi:10.1016/j.paid.2016.09.018

Diurnal coupling between testosterone and cortisol from adolescence to older adulthood

K. Paige Harden, Cornelia Wrzus, Gloria Luong, Andrew Grotzinger, Malek Bajbouj, Antje Rauers, Gert G. Wagner, Michaela Riediger

Psychoneuroendocrinology  ·  01 Nov 2016  ·  doi:10.1016/j.psyneuen.2016.07.216

Sensation seeking, peer deviance, and genetic influences on adolescent delinquency: Evidence for person-environment correlation and interaction.

Frank D. Mann, Megan W. Patterson, Andrew D. Grotzinger, Natalie Kretsch, Jennifer L. Tackett, Elliot M. Tucker-Drob, K. Paige Harden

Journal of Abnormal Psychology  ·  01 Jul 2016  ·  doi:10.1037/abn0000160

Anorexia nervosa, emotional go/no‐go, and the distinct effect of testosterone

Tom Hildebrandt, Andrew Grotzinger, Kurt Schulz

International Journal of Eating Disorders  ·  31 Aug 2015  ·  doi:10.1002/eat.22456

Testing the disgust conditioning theory of food-avoidance in adolescents with recent onset anorexia nervosa

Tom Hildebrandt, Andrew Grotzinger, Marianne Reddan, Rebecca Greif, Ifat Levy, Wayne Goodman, Daniela Schiller

Behaviour Research and Therapy  ·  01 Aug 2015  ·  doi:10.1016/j.brat.2015.06.008

The benefits of using semi‐continuous and continuous models to analyze binge eating data: A Monte Carlo investigation

Andrew Grotzinger, Tom Hildebrandt, Jessica Yu

International Journal of Eating Disorders  ·  05 Sep 2014  ·  doi:10.1002/eat.22351